Gamma Globulin medical wonders

Human blood is an essential body fluid that carries oxygen and other important nutrients to all the body cells. It is also responsible for flushing out of carbon dioxide, ammonia, and other waste products from the human body. This fluid contributes almost 7-8% of human body weight and plays a vital role in maintaining a constant body temperature. It also helps the immune system in defense against the various attacks to diseases from external sources. Human Blood is a highly specialized tissue composed of more than 4,000 different kinds of components.  Four of the most important Blood Products are red cells, white cells, platelets, and plasma.  All these Human Blood Products helps in maintain the human life cycle and fight against various diseases and ailments.

Gamma Globulin is also one of such Human Blood Products that is produced in the liver, while some are made by the immune system. They are a class of globulins, identified by their position after serum protein electrophoresis is done, which is a laboratory test that examines specific proteins in the blood called globulins. The most significant gamma globulins are immunoglobulins or Igs, more commonly known as antibodies. However, some Igs are not gamma globulins, and some gamma globulins are not Igs.

Gamma Globulin is also one of the types of globulins that are produced without any previous infection, vaccination, other foreign antigen exposure in the liver of humans. These antibodies can activate the classical complement pathway leading to lysis of enveloped virus particles long before the adaptive immune response is activated. They are very beneficial when produced in the human body for fighting against all the viruses and diseases.

Generally all humans produce these Human Blood Products irrespective of location or gender. But sometimes there is an excess production of these substances in the human blood which at times can be harmful to the human body. An excess production of Gamma Globulin in human serum is known as ‘Hypergammaglobulinemia’. Also, sometimes there is scarcity of production in the body due this deficiency is known as ‘Hypogammaglobulinemia’. Either it is in excess or deficient human body is prone to a disease called "gammopathy".

However, these substances can be extracted from healthy donors and can be utilized for preparing medications and therapies that can come useful to patients that are suffering from diseases like gammopathy, or any other chronic disease. Gamma Globulin injections are usually given to temporarily boost a patient's immunity against various diseases and also are given along with blood transfusions and intravenous drug use, to pass along Hepatitis C to the patients. These injections are most commonly used on patients having been exposed to hepatitis A or measles, or to make a kidney donor and recipient compatible regardless of blood type of tissue match. These Injections are also used to boost immunity in patients who are unable to produce gamma globulins naturally in their body because of an immune deficiency, such as X-linked agammaglobulinemia and hyper IgM syndrome. Such injections are less common in modern medical practice than they were previously used as they are now replaced by the use of hepatitis A vaccine instead.

Gamma globulin infusions are also used to treat some immunological diseases, such as idiopathic thrombocytopenia purpura (ITP), a disease in which the platelets are being attacked by antibodies, leading to seriously low platelet counts. It appears that they cause the spleen to ignore the antibody tagged platelets, thus allowing them to survive and function properly.

Irrespective of its type and quantity these Human Blood Products are working wonders in medical world by helping in development of various medications, therapies and vaccines to help save many human lives around the globe.

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Human Blood Albumen significance

Blood products are widely used to replace blood or particular components of the blood that have been lost by accident or illness in the human body. These products can be extracted from the human blood and used for the medication purpose for many ailing and life fighting patents and also for transfusion purpose. All blood products are made from blood collected from volunteer blood donors that donate their blood and all other such Human Blood Products for the help of researches and medicine development purposes.

Human Serum Albumin is also one of such rare element that has proven to be very useful in development of various medicines and therapies. It is also one of the major constituent of human blood which when extracted can be very useful for the development of various medicines and vaccines.

Albumins are commonly found in blood plasma, and are unique from other blood proteins as they are not glycosylated in nature.  is the most abundant protein in human blood plasma which is produced in the liver of human body. Albumin constitutes about half of the blood serum protein and is responsible for the transport of all hormones, fatty acids, and other compounds, buffers pH, and for maintaining osmotic pressure, among other major functions of the human body.

Albumins are soluble and monomeric in nature. These when extracted are preserved in the powdered form for the future use, for the development of medicines and various therapies. Human Serum Albumin is available for medical use, usually at concentrations of 5-25% as the albumen levels can affect the life of drugs to some extent. Also, an excess and lack of albumin can have very bad effect on the human body.

Human Serum Albumin is very essential for maintaining the osmotic pressure needed for proper distribution of body fluids between all the body tissues and parts of the body. This substance acts as a plasma carrier by nonspecifically binding several hydrophobic steroid hormones and as a transport protein for hemin and fatty acids throughout the human body. However excess serum albumin in the body can be harmful though. Human Serum Albumin is often used to replace lost fluid and help restore blood volume in trauma, burns and surgery patients. This is preserved for all such future medical and research uses.

All these Human Blood Products when extracted from the human body cause no harm to the donors, and can be easily regenerated in the body within small period of time. Though after the donation the donor may face little of dizziness or discomfort, which is though very minor at times. All these Human Blood Products are very useful in the preparation of medications or drugs for some of the rare and chronic diseases throughout the world. Many therapies and vaccines are made using these products from the human blood. These substances works wonders when present in the body by providing the accurate flow of blood and plasma in the human body and when taken out works as a life saving substance for many dangerous and chronic diseases.

While such transmissions and extractions with zero risk of transmitting infectious disease may not be possible, but with the development of latest technologies least possible risk are being recorded as all the transmissions are tested for such issues and least possible issues or side effects are attained. As Human Blood Products are likely always to carry an inherent risk of infectious agents zero risk may be unattainable. The role of new donor locations is to drive that risk to the lowest level reasonably achievable without unduly decreasing the availability of this life saving resource and its medical quality.

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Human Serum donation for a good cause

Human Serum is the elementary part of human blood which is not a blood cell and also not a clotting factor, but simply the plasma without the fibrinogens in it. Fibrinogen is a protein in the plasma that is essential for the coagulation of blood and is converted to fibrin by thrombin and ionized calcium, also the clotting factor of it. Serum does not contain all the proteins that are responsible for coagulation or the clotting. Also, it does not have the essential components which are required for antibodies, hormones and other microorganisms.

Being a part of human blood serum does not contain any WBC or RBC in it. Though, it is very essential factor for the self renewal of embryonic stem cells in combination with the cytokine leukemia inhibitory factor. These were all the medical facts, but talking in general people are donating the blood, plasma as well the human serum. This without causing any harm to the donor is working as a life saving substance for many ailing people.

These Human Blood Products are proving to be very useful in the preparation of medications or drugs for some of the rare and chronic diseases. Many therapies are made using these products from the body. These substances works wonders when present in the body by providing the accurate flow of blood in the human body and when taken out works as a life saving substance for many diseases like cancer, tumors etc.

Serum Donation is not though very common yet like other donation, but many people around the globe are now coming forward for such donations either for money or as a noble deed. There are many camps or clinics set up for taking this out from the human body. Serum Donation can prove to be a very helpful cause for saving many lives.

Human Serum is extracted from the body in these clinics with the help of a gel tube with a clotting accelerator attached to it. The blood is collected and rested till clotting starts for about 20 to 30 minutes in general, but which accelerator it will be done more quickly and then the serum is separated from it, as this part do not clot with the blood. When it is extracted and kept on centrifugation at 1500g for 10 minutes, it pulls the required cells below the gel layer which can be taken out easily now. It is then effectively sealed off from the cells and is stored at 4 degrees Celsius. Then with an automated method ‘immunoturbidimetry’ which is traceable to the CRM 470 (Reference Preparation for Proteins in Serum) it is being sampled and forwarded for the medication use.

All these Human Blood Products when extracted from the body cause no harm to the donors, and can be easily regenerated in the body within short span of time. Though post the extraction process the donor may face little of dizziness or discomfort, which is though very minor. Drinking of fluids like juice and water before the donation is advisable to cause less discomfort to the donor.

About Access Biologicals: Access Biologicals is a leading source for Biological Products with access to Plasma and serum Donation centers that have been donating specialty human based Biological Products to meet your specifications. Learn more about Access Biologicals by visiting at http://www.accessbiologicals.com/