Monday, 1 October 2012

Medical usage of Plasma Products



Biological products like all the other drugs are widely used in the treatment of various diseases in humans. Biological products are generally derived from living creatures like human, animal, or microorganism and are complex in structure, and thus are usually not fully characterized in nature. There are many such Biological Products that come to be very useful for developing various medications when they are extracted from the human body and can be used for the cure of various ailments.

Human plasma is also of such product that is present in the human blood. It is a combination of various proteins and other substances which are very crucial for the smooth running of human bodies. This is the liquid part of the blood and majorly responsible for the smooth flow of blood throughout the body. When it is extracted, its proteins and other beneficial substances are used as the development of medical products made to replace body fluids, antibodies and clotting factors in the human body. This is a lifesaving resource that benefits thousands of people every day.

Some of the medical uses of human plasma and products made from it:

·         Plasma Products are used in surgery and the treatment of wounds to facilitate fast healing.
·         Plasma Products are used in the treatment of immunological disorders, such as congenital and acquired primary immune deficiency as well as many other diseases that affects healthy people due to some change in the body’s immune system.
·         Since it is the liquid part of blood with all the clotting factors included in it, people with clotting factor deficiencies can receive replacement clotting factors harvested from such products.
·         Patients who overdose on their blood thinning medication can also benefit from a plasma transfusion to offset the effects of such high medication dosages.
·         People who undergo terrible medical conditions also receive this product to help prevent the development of medical complications in future.
·         It is used to replace lost fluids and other blood proteins in burn victims. As the body tries to recover from the effects of burns, and as the skin loses its ability to restore body fluids, the body transfers blood fluids out of circulation and into the skin tissues for its fast recovery. Plasma products help in replacing the lost body fluids and also in restore.
·         One important protein obtained from it is albumin that is also very useful in creating medicines. This product can be given to surgical patients or accident victims in the case of major blood loss.
·         Patients can also receive extra protein from plasma transfusions.
·         This also has specific antibodies that can be helpful in fighting off conditions like cirrhosis or emphysema.
·         Such products are also used in many clinical researches for creating vaccines, therapies and medications to fight against various life taking chronic diseases like HIV, tumors and cancer etc.

When blood plasma is collected from donors, it is immediately frozen to keep its properties fresh. It stays frozen at the clinic where it was collected, and is stored and transported frozen. When it arrives at the location where it is to be administered to a patient, it is thawed out completely. Frozen plasma can be stored up to 10 years, making it an extremely stable blood product, and it can also be packaged in dried form for reconstitution, a technique which was developed for military applications.

All the Biological products and plasma products are very useful in saving lives of many people around the world. Every individual must understand its importance and should give donation of such substances that can save life of their fellow beings without causing any harm to them.

Learn more about such Biological products by visiting at http://www.accessbiologicals.com

Tuesday, 18 September 2012

Human Blood Albumen significance



Blood products are widely used to replace blood or particular components of the blood that have been lost by accident or illness in the human body. These products can be extracted from the human blood and used for the medication purpose for many ailing and life fighting patents and also for transfusion purpose. All blood products are made from blood collected from volunteer blood donors that donate their blood and all other such Human Blood Products for the help of researches and medicine development purposes.

Human Serum Albumin is also one of such rare element that has proven to be very useful in development of various medicines and therapies. It is also one of the major constituent of human blood which when extracted can be very useful for the development of various medicines and vaccines.

Albumins are commonly found in blood plasma, and are unique from other blood proteins as they are not glycosylated in nature.  is the most abundant protein in human blood plasma which is produced in the liver of human body. Albumin constitutes about half of the blood serum protein and is responsible for the transport of all hormones, fatty acids, and other compounds, buffers pH, and for maintaining osmotic pressure, among other major functions of the human body.

Albumins are soluble and monomeric in nature. These when extracted are preserved in the powdered form for the future use, for the development of medicines and various therapies. Human Serum Albumin is available for medical use, usually at concentrations of 5-25% as the albumen levels can affect the life of drugs to some extent. Also, an excess and lack of albumin can have very bad effect on the human body.

Human Serum Albumin is very essential for maintaining the osmotic pressure needed for proper distribution of body fluids between all the body tissues and parts of the body. This substance acts as a plasma carrier by nonspecifically binding several hydrophobic steroid hormones and as a transport protein for hemin and fatty acids throughout the human body. However excess serum albumin in the body can be harmful though. Human Serum Albumin is often used to replace lost fluid and help restore blood volume in trauma, burns and surgery patients. This is preserved for all such future medical and research uses.


All these Human Blood Products when extracted from the human body cause no harm to the donors, and can be easily regenerated in the body within small period of time. Though after the donation the donor may face little of dizziness or discomfort, which is though very minor at times. All these Human Blood Products are very useful in the preparation of medications or drugs for some of the rare and chronic diseases throughout the world. Many therapies and vaccines are made using these products from the human blood. These substances works wonders when present in the body by providing the accurate flow of blood and plasma in the human body and when taken out works as a life saving substance for many dangerous and chronic diseases.

While such transmissions and extractions with zero risk of transmitting infectious disease may not be possible, but with the development of latest technologies least possible risk are being recorded as all the transmissions are tested for such issues and least possible issues or side effects are attained. As Human Blood Products are likely always to carry an inherent risk of infectious agents zero risk may be unattainable. The role of new donor locations is to drive that risk to the lowest level reasonably achievable without unduly decreasing the availability of this life saving resource and its medical quality.

Learn more about such Biological products by visiting at http://www.accessbiologicals.com/

Saturday, 8 September 2012

Globulins of the human blood



In the human biochemistry study, the blood components are widely divided. Human plasma being one of the important constituent is majorly responsible for the accurate flow of blood in the human body. Human plasma is made up of water and proteins and occupies almost 55% of total blood volume in the human body. However this substance is a regenerating substance in the body which can be easily formed again by it, so can be donated for medication or research purposes without causing any deficiency to the body.

In the human plasma there are 3 types of serum proteins present albumin, fibrinogen and Globulin. When the fibrinogen is separated from the plasma it becomes the serum part. Fibrinogen is the clotting part of the blood. Albumin is also a globular protein, but not a globulin. All other serum globular proteins except the albumin are globulins. Some globulins are produced in the liver, while others are produced by the immune system of the human body.

The serum globulins are categorized into 4 types based on its properties. Protein electrophoresis is the method which is used to categorize these serum globulins into the following four categories:

·         Alpha 1 globulins
·         Alpha 2 globulins
·         Beta globulins
·         Gamma globulins


Alpha globulins are a group of the globular proteins that are very volatile in an electrically charged solution or the alkaline solutions. These alpha globulins withhold several blood enzymes in it. There are various types of alpha globulins which are further divided into Alpha 1 and Alpha 2.

Beta globulins are also same like the Alpha globulins but are less volatile when compared to them. This is a globulin in blood plasma that carries iron and are transport proteins, serving as a substrates upon which other substances are formed, and perform other diverse functions in the human body.

Gamma globulins are the type of globulins that are identified by their position after the process electrophoresis is done for the extraction of serum protein. These are the antibodies which are very crucial in the development of various medications and therapeutic use. Being the heaviest, they are the slowest to segregate in Electrophoresis. Since they are immunologically active, they are also called as Immunoglobulin. These are very important part of human blood as their excess and deficiency both are not good for health and can cause a disease called "gammopathy". An excess of it is called as “hypergammaglobulinemia” whereas deficiency is called as “hypogammaglobulinemia”.

Injections are given to the patients to boost immunity in patients who are unable to produce the required gamma globulins quantity naturally because of an immune deficiency. Such injections are less common in modern medical practice than they were previously, as they have been replaced by the use of hepatitis A vaccine. However, being a substance taken from blood, gamma globulin injections, along with blood transfusions and intravenous drug use, could pass along Hepatitis C to its recipient, which is the major cause of its replacement in the medical use. Apart from gamma globulins, there are medications available foe alpha and bets too in the world which can be taken.

Learn more about such Biological products by visiting at http://www.accessbiologicals.com/

Friday, 31 August 2012

Biological Products donation for medical use



Biological Products include a wide range of things like vaccines, blood and blood components, which are created by biologic processes, rather than being chemically synthesized. These products are extracted from the human body and sterilized for the future use in medications and researches. These products on the prominence are very helpful to the biomedical research, and also used for developing medications to treat variety of medical conditions for which no other treatments are available. There are many such human products that can be used for the researches and in developing therapies, and especially many clinics are also being set up for this purpose. People all over the globe are now coming forward to donate these biological products for the betterment of medical sciences and researches.

Human plasma and serum are also such imperative substances that are very much needed in the medical researches and in the development of medications to cure some of the rare chronic diseases. Human blood products like serum and other are very helpful in creating treatments or medications for diseases that attack the immune system like HIV and cancer etc. Donating Plasma can really prove to be a sinful deed as this can save lives of many needful people who are fighting with life taking diseases. Be it blood or Serum Donation you are even get paid for it.

Let’s see what these two substances are actually:

Plasma is a yellowish liquid of the human blood that carries all the essential substances to the entire human body. It is being extracted from the human blood through “Plasmapheresis”. This method is used to collect it at the frozen state and is preserved for future use in the manufacture of a variety of medications. Donating Plasma can help in manufacturing of all such medications which are very difficult to find in the whole world.

Human Serum is the elementary part of human blood which is not a blood cell and also not a clotting factor, but simply the plasma without the fibrinogens in it. Fibrinogen is a protein in the plasma which is essential for the coagulation of blood and is converted to fibrin by thrombin and ionized calcium, also the clotting factor of it. Being a part of human blood it does not contain any WBC or RBC in it. This is extracted from the body in these clinics with the help of a gel tube by clotting the blood and separating it from it. Serum Donation is also rising as many people donate these substances to earn some dollars.

All these Biological products including blood and blood products are likely always to carry an inherent risk of infectious agents in them. These clinics make your donation go through various tests in order to decrease the risk factor without decreasing the quality of this life saving substance. Donating plasma and Serum Donation though cause minor of side effects to the donor like little of dizziness and nausea. However, these are the regenerating substances, which can grow back once you donate them with in short span of time. Persons above 18 years of age can only donate plasma and serum. Underweight people are strictly not recommended for such donations.
About Access Biologicals: Access Biologicals is a leading source for Biological Products with access to Plasma and serum Donation centers that have been donating specialty human based Biological Products to meet your specifications. Learn more about Access Biologicals by visiting at http://www.accessbiologicals.com/